The role of adenosine as a cardioprotective agent is well known and recent experimental studies suggest that impairment of adenosine-related signal transduction contributes to the pathophysiology of chronic heart failure. The recent observation of an association between ADA, genetic polymorphism and coronary artery disease (CAD) prompted us to study the possible relevance of three intragenic polymorphic sites of the ADA gene (ADA1, ADA2 and ADA6).

Saccucci, P., Binczak Kuleta, A., Banci, M., Krzysztalowska, M., Dofcaci, A., Safranow, K., et al. (2014). Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene. ACTA CARDIOLOGICA, 69(1), 39-44.

Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene

SACCUCCI, PATRIZIA;MAGRINI, ANDREA;BOTTINI, EGIDIO;
2014-02-01

Abstract

The role of adenosine as a cardioprotective agent is well known and recent experimental studies suggest that impairment of adenosine-related signal transduction contributes to the pathophysiology of chronic heart failure. The recent observation of an association between ADA, genetic polymorphism and coronary artery disease (CAD) prompted us to study the possible relevance of three intragenic polymorphic sites of the ADA gene (ADA1, ADA2 and ADA6).
feb-2014
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/44 - MEDICINA DEL LAVORO
English
Con Impact Factor ISI
Sex Factors; Polymorphism, Genetic; Humans; Infant, Newborn; Aged; Italy; Ethnic Groups; Poland; Middle Aged; Adenosine Deaminase; Genetic Predisposition to Disease; Coronary Artery Disease; Female; Male
Saccucci, P., Binczak Kuleta, A., Banci, M., Krzysztalowska, M., Dofcaci, A., Safranow, K., et al. (2014). Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene. ACTA CARDIOLOGICA, 69(1), 39-44.
Saccucci, P; Binczak Kuleta, A; Banci, M; Krzysztalowska, M; Dofcaci, A; Safranow, K; Magrini, A; Loniewska, B; Kornacewicz Jach, Z; Chlubek, D; Botti...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/85687
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