Fabrication of multifunctional ultrasound contrast agents (UCAs) has been recently addressed by several research groups. A versatile strategy for the synthesis of UCA precursors in the form of biodegradable vesicles with a biocompatible crosslinked polymer shell is described. Upon ultrasound irradiation, acoustic droplet vaporization transforms such particles into microbubbles behaving as UCAs. This proof of concept entails the features of a potential theranostic microdevice.

Capece, S., Chiessi, E., Cavalli, R., Giustetto, P., Grishenkov, D., Paradossi, G. (2013). A general strategy for obtaining biodegradable polymer shelled microbubbles as theranostic devices. CHEMICAL COMMUNICATIONS, 49(51), 5763-5765 [10.1039/c3cc42037j].

A general strategy for obtaining biodegradable polymer shelled microbubbles as theranostic devices

CHIESSI, ESTER;PARADOSSI, GAIO
2013-01-01

Abstract

Fabrication of multifunctional ultrasound contrast agents (UCAs) has been recently addressed by several research groups. A versatile strategy for the synthesis of UCA precursors in the form of biodegradable vesicles with a biocompatible crosslinked polymer shell is described. Upon ultrasound irradiation, acoustic droplet vaporization transforms such particles into microbubbles behaving as UCAs. This proof of concept entails the features of a potential theranostic microdevice.
2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore CHIM/02 - CHIMICA FISICA
English
Capece, S., Chiessi, E., Cavalli, R., Giustetto, P., Grishenkov, D., Paradossi, G. (2013). A general strategy for obtaining biodegradable polymer shelled microbubbles as theranostic devices. CHEMICAL COMMUNICATIONS, 49(51), 5763-5765 [10.1039/c3cc42037j].
Capece, S; Chiessi, E; Cavalli, R; Giustetto, P; Grishenkov, D; Paradossi, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/84882
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