By combining DNA probes having different target affinities, but with similar specificity on the same electrode, an extended dynamic response of a biosensor spanning three orders of magnitude in target concentration was obtained. By using a different strategy, the useful dynamic range of an electrochemical DNA sensor was narrowed to only an 8-fold range of target concentrations.
Kang, D., Vallée Bélisle, A., Porchetta, A., Plaxco, K., Ricci, F. (2012). Re-engineering Electrochemical Biosensors To Narrow or Extend Their Useful Dynamic Range. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 51(27), 6717-6721 [10.1002/anie.201202204].
Re-engineering Electrochemical Biosensors To Narrow or Extend Their Useful Dynamic Range
Porchetta, A;RICCI, FRANCESCO
2012-01-01
Abstract
By combining DNA probes having different target affinities, but with similar specificity on the same electrode, an extended dynamic response of a biosensor spanning three orders of magnitude in target concentration was obtained. By using a different strategy, the useful dynamic range of an electrochemical DNA sensor was narrowed to only an 8-fold range of target concentrations.| File | Dimensione | Formato | |
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