Rapid and early virological responses to peginterferon-alpha and ribavirin are predictive of sustained virological response (SVR) in hepatitis C virus (HCV) infection. We aimed at finding a simple rule to determine the shortest duration of dual therapy for all HCV genotypes, obtained by multiplying time to Initial Viral Response, IVR (first undetectable HCV-RNA) by 4 (Tailored Therapy-4, or TT4).

Francioso, S., Almerighi, C., Forte, P., Bandiera, F., Nosotti, L., Lionetti, R., et al. (2014). A simple rule to personalize standard dual therapy across all genotypes in naive chronic hepatitis C patients: The TT4 randomized trial. DIGESTIVE AND LIVER DISEASE, 46(2), 164-169 [10.1016/j.dld.2013.10.002].

A simple rule to personalize standard dual therapy across all genotypes in naive chronic hepatitis C patients: The TT4 randomized trial

FRANCIOSO, SIMONA;SALSO, ANGELA;RENZI, SIMONE;ANGELICO, MARIO
2014-02-01

Abstract

Rapid and early virological responses to peginterferon-alpha and ribavirin are predictive of sustained virological response (SVR) in hepatitis C virus (HCV) infection. We aimed at finding a simple rule to determine the shortest duration of dual therapy for all HCV genotypes, obtained by multiplying time to Initial Viral Response, IVR (first undetectable HCV-RNA) by 4 (Tailored Therapy-4, or TT4).
feb-2014
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/12 - GASTROENTEROLOGIA
English
Con Impact Factor ISI
Rapid viral response; Individualized therapy; Ribavirin; Response-guided therapy; Pegylated interferon; Dual therapy; HCV treatment
Francioso, S., Almerighi, C., Forte, P., Bandiera, F., Nosotti, L., Lionetti, R., et al. (2014). A simple rule to personalize standard dual therapy across all genotypes in naive chronic hepatitis C patients: The TT4 randomized trial. DIGESTIVE AND LIVER DISEASE, 46(2), 164-169 [10.1016/j.dld.2013.10.002].
Francioso, S; Almerighi, C; Forte, P; Bandiera, F; Nosotti, L; Lionetti, R; Taliani, G; Piras, M; Ponti, M; Parruti, G; Di Candilo, F; Gentile, S; Pic...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/83656
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