Wearing-off (WO) refers to the exacerbation of motor and/or non-motor symptoms of Parkinson's disease at the end of dose of dopaminergic medications. Treatment of WO is based on modifying drug schedule, meal timetable and/or increasing dopamine replacement therapy. In advanced and/or demented patients, management of WO is often limited by scarce compliance and by cognitive, psychiatric and dysautonomic side-effects that may accompany increased dopaminergic stimulation.

Fanciulli, A., Assogna, F., Caltagirone, C., Spalletta, G., Pontieri, F. (2013). Rotigotine for anxiety during wearing-off in Parkinson's disease with dementia, 25(5), 601-603 [10.1007/s40520-013-0136-4].

Rotigotine for anxiety during wearing-off in Parkinson's disease with dementia

CALTAGIRONE, CARLO;
2013-10-01

Abstract

Wearing-off (WO) refers to the exacerbation of motor and/or non-motor symptoms of Parkinson's disease at the end of dose of dopaminergic medications. Treatment of WO is based on modifying drug schedule, meal timetable and/or increasing dopamine replacement therapy. In advanced and/or demented patients, management of WO is often limited by scarce compliance and by cognitive, psychiatric and dysautonomic side-effects that may accompany increased dopaminergic stimulation.
ott-2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26 - NEUROLOGIA
English
Fanciulli, A., Assogna, F., Caltagirone, C., Spalletta, G., Pontieri, F. (2013). Rotigotine for anxiety during wearing-off in Parkinson's disease with dementia, 25(5), 601-603 [10.1007/s40520-013-0136-4].
Fanciulli, A; Assogna, F; Caltagirone, C; Spalletta, G; Pontieri, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/83127
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