In multiple sclerosis (MS), the location of focal lesions does not always correlate with clinical symptoms, suggesting disconnection as a major pathophysiological mechanism. Resting-state (RS) functional magnetic resonance imaging (fMRI) is believed to reflect brain functional connectivity (FC) within specific neuronal networks.
Basile, B., Castelli, M., Monteleone, F., Nocentini, U., Caltagirone, C., Centonze, D., et al. (2013). Functional connectivity changes within specific networks parallel the clinical evolution of multiple sclerosis. MULTIPLE SCLEROSIS [10.1177/1352458513515082].
Functional connectivity changes within specific networks parallel the clinical evolution of multiple sclerosis
MONTELEONE, FABRIZIA;NOCENTINI, UGO;CALTAGIRONE, CARLO;CENTONZE, DIEGO;
2013-12-10
Abstract
In multiple sclerosis (MS), the location of focal lesions does not always correlate with clinical symptoms, suggesting disconnection as a major pathophysiological mechanism. Resting-state (RS) functional magnetic resonance imaging (fMRI) is believed to reflect brain functional connectivity (FC) within specific neuronal networks.File in questo prodotto:
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