Background: According to Italian legislation to diagnose brain death (BD) after the initial documentation of the clinical signs, repetition of clinical testing and confirmation of the loss of bioelectrical activity of the brain (EEG) is required. However, when EEG is unreliable it is necessary to demonstrate cerebral circulatory arrest (CCA). Accepted imaging techniques to demonstrate CCA include: cerebral angiography, cerebral scintigraphy, transcranial Doppler (TCD) and computed tomography angiography (CTA). This latter technique, due to its large availability, low invasivity and easy and fast acquisition is widely used over the country. Nevertheless its diagnostic reliability is affected by some limitations in patients with decompressive craniectomy. Methods and Results: Here we report two cases of brain injury with clinical signs of BD and at the same time, opacification of intracranial arteries on CTA and a pattern consistent with flow arrest on the corresponding insonable arteries on TCD. Conclusion: The discrepancy between CTA and TCD results points out a methodology limitation that could be overcome by updating Italian legislation according to other European Countries legislation.

Frisardi, F., Stefanini, M., Natoli, S., Cama, V., Loreni, G., Di Giuliano, F., et al. (2013). Decompressive craniectomy may cause diagnostic challenges to asses brain death by computed tomography angiography. MINERVA ANESTESIOLOGICA.

Decompressive craniectomy may cause diagnostic challenges to asses brain death by computed tomography angiography.

NATOLI, SILVIA;Di Giuliano F;LEONARDIS, CARLO;DAURI, MARIO;SABATO, ALESSANDRO FABRIZIO;SIMONETTI, GIOVANNI MARIA EGISTO;LEONARDIS, FRANCESCA
2013-05-23

Abstract

Background: According to Italian legislation to diagnose brain death (BD) after the initial documentation of the clinical signs, repetition of clinical testing and confirmation of the loss of bioelectrical activity of the brain (EEG) is required. However, when EEG is unreliable it is necessary to demonstrate cerebral circulatory arrest (CCA). Accepted imaging techniques to demonstrate CCA include: cerebral angiography, cerebral scintigraphy, transcranial Doppler (TCD) and computed tomography angiography (CTA). This latter technique, due to its large availability, low invasivity and easy and fast acquisition is widely used over the country. Nevertheless its diagnostic reliability is affected by some limitations in patients with decompressive craniectomy. Methods and Results: Here we report two cases of brain injury with clinical signs of BD and at the same time, opacification of intracranial arteries on CTA and a pattern consistent with flow arrest on the corresponding insonable arteries on TCD. Conclusion: The discrepancy between CTA and TCD results points out a methodology limitation that could be overcome by updating Italian legislation according to other European Countries legislation.
23-mag-2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/41 - ANESTESIOLOGIA
Settore MED/26 - NEUROLOGIA
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
English
Con Impact Factor ISI
Frisardi, F., Stefanini, M., Natoli, S., Cama, V., Loreni, G., Di Giuliano, F., et al. (2013). Decompressive craniectomy may cause diagnostic challenges to asses brain death by computed tomography angiography. MINERVA ANESTESIOLOGICA.
Frisardi, F; Stefanini, M; Natoli, S; Cama, V; Loreni, G; Di Giuliano, F; Fiume, D; Leonardis, C; Dauri, M; Sabato, Af; Simonetti, Gme; Leonardis, F...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/82568
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