Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.

Ricci, F., Staurenghi, G., Lepre, T., Missiroli, F., Zampatti, S., Cascella, R., et al. (2013). Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study. PLOS ONE, 8(6) [10.1371/journal.pone.0066978].

Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study

RICCI, FEDERICO;MISSIROLI, FILIPPO;BORGIANI, PAOLA;MARSELLA, LUIGI TONINO;NOVELLI, GIUSEPPE;GIARDINA, EMILIANO
2013

Abstract

Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/43 - Medicina Legale
English
macular degeneration; IL-8 allele; genetic factors; inflammation and angiogenesis
Ricci, F., Staurenghi, G., Lepre, T., Missiroli, F., Zampatti, S., Cascella, R., et al. (2013). Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study. PLOS ONE, 8(6) [10.1371/journal.pone.0066978].
Ricci, F; Staurenghi, G; Lepre, T; Missiroli, F; Zampatti, S; Cascella, R; Borgiani, P; Marsella, Lt; Eandi, C; Cusumano, A; Novelli, G; Giardina, E
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration A Case-Control Study.pdf

non disponibili

Licenza: Copyright dell'editore
Dimensione 160.12 kB
Formato Adobe PDF
160.12 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/79950
Citazioni
  • ???jsp.display-item.citation.pmc??? 18
  • Scopus 24
  • ???jsp.display-item.citation.isi??? 24
social impact