Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.

Ricci, F., Staurenghi, G., Lepre, T., Missiroli, F., Zampatti, S., Cascella, R., et al. (2013). Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study. PLOS ONE, 8(6) [10.1371/journal.pone.0066978].

Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study

RICCI, FEDERICO;MISSIROLI, FILIPPO;BORGIANI, PAOLA;MARSELLA, LUIGI TONINO;NOVELLI, GIUSEPPE;GIARDINA, EMILIANO
2013-01-01

Abstract

Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.
2013
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/43 - MEDICINA LEGALE
English
macular degeneration; IL-8 allele; genetic factors; inflammation and angiogenesis
Ricci, F., Staurenghi, G., Lepre, T., Missiroli, F., Zampatti, S., Cascella, R., et al. (2013). Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study. PLOS ONE, 8(6) [10.1371/journal.pone.0066978].
Ricci, F; Staurenghi, G; Lepre, T; Missiroli, F; Zampatti, S; Cascella, R; Borgiani, P; Marsella, Lt; Eandi, C; Cusumano, A; Novelli, G; Giardina, E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/79950
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