Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.
Ricci, F., Staurenghi, G., Lepre, T., Missiroli, F., Zampatti, S., Cascella, R., et al. (2013). Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study. PLOS ONE, 8(6) [10.1371/journal.pone.0066978].
Haplotypes in IL-8 gene are associated to age-related macular degeneration: a case-control study
RICCI, FEDERICO;MISSIROLI, FILIPPO;BORGIANI, PAOLA;MARSELLA, LUIGI TONINO;NOVELLI, GIUSEPPE;GIARDINA, EMILIANO
2013-01-01
Abstract
Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.| File | Dimensione | Formato | |
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Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration A Case-Control Study.pdf
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