The aim of the present study was to investigate the genetic variability of VKORC1, CYP2C9 and CYP4F2 genes in patients who required a very low and high warfarin dose, in order to identify novel variants that could help to explain the particular extreme dose requirements.

Di Fusco, D., Ciccacci, C., Rufini, S., Forte, V., Novelli, G., Borgiani, P. (2013). Resequencing of VKORC1, CYP2C9 and CYP4F2 genes in Italian patients requiring extreme low and high warfarin doses. THROMBOSIS RESEARCH, 132(1), 123-126 [10.1016/j.thromres.2013.05.002].

Resequencing of VKORC1, CYP2C9 and CYP4F2 genes in Italian patients requiring extreme low and high warfarin doses

CICCACCI, CINZIA;FORTE, VIVIANA;NOVELLI, GIUSEPPE;BORGIANI, PAOLA
2013-07-01

Abstract

The aim of the present study was to investigate the genetic variability of VKORC1, CYP2C9 and CYP4F2 genes in patients who required a very low and high warfarin dose, in order to identify novel variants that could help to explain the particular extreme dose requirements.
lug-2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/03 - GENETICA MEDICA
English
CYP2C9; Polymorphism; VKORC1; Warfarin; CYP4F2; Pharmacogenetics
Di Fusco, D., Ciccacci, C., Rufini, S., Forte, V., Novelli, G., Borgiani, P. (2013). Resequencing of VKORC1, CYP2C9 and CYP4F2 genes in Italian patients requiring extreme low and high warfarin doses. THROMBOSIS RESEARCH, 132(1), 123-126 [10.1016/j.thromres.2013.05.002].
Di Fusco, D; Ciccacci, C; Rufini, S; Forte, V; Novelli, G; Borgiani, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/79798
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