Microdialysis coupled to a glucose biosensor led to a continuous monitor system in vivo for glucose. Several microdialysis probes were used to stabilize the biosensor response. In vivo experiments, especially when the probe was placed subcutaneously, showed that the sensitivity of the biosensor decreased continuously; various kinds of fibers with a molecular weight cut-off (MWCO) ranging from 6 000 to 20 000 were compared. A wall-jet flow cell as detector for glucose showed less interference when compared to a thin layer cell. Glucoday, a new commercial instrument based on this principle, is presented.
MOSCONE DINIA, D., Mascini, M. (1992). Microdialysis and glucose biosensor for in-vivo monitoring. ANNALES DE BIOLOGIE CLINIQUE, 50(5), 323-327.
Microdialysis and glucose biosensor for in-vivo monitoring
MOSCONE DINIA, DANILA;
1992-01-01
Abstract
Microdialysis coupled to a glucose biosensor led to a continuous monitor system in vivo for glucose. Several microdialysis probes were used to stabilize the biosensor response. In vivo experiments, especially when the probe was placed subcutaneously, showed that the sensitivity of the biosensor decreased continuously; various kinds of fibers with a molecular weight cut-off (MWCO) ranging from 6 000 to 20 000 were compared. A wall-jet flow cell as detector for glucose showed less interference when compared to a thin layer cell. Glucoday, a new commercial instrument based on this principle, is presented.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
