Insulin-like growth factor-II (IGF-II), traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator. The aim of this overview is to provide the available evidence, obtained in both experimental conditions and in humans, for a role of IGF-II in the fine-tuning of metabolism and body composition. The underlying mechanisms and the potential clinical implications are discussed.
Cianfarani, S. (2012). Insulin-like growth factor-II: new roles for an old actor. FRONTIERS IN ENDOCRINOLOGY, 3, 118 [10.3389/fendo.2012.00118].
Insulin-like growth factor-II: new roles for an old actor
CIANFARANI, STEFANO
2012-01-01
Abstract
Insulin-like growth factor-II (IGF-II), traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator. The aim of this overview is to provide the available evidence, obtained in both experimental conditions and in humans, for a role of IGF-II in the fine-tuning of metabolism and body composition. The underlying mechanisms and the potential clinical implications are discussed.File in questo prodotto:
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