Although TNF-α blockade is a very effective therapy for psoriasis, not all patients achieve a favorable outcome. The association between IL-6 and psoriasis has been investigated but no papers have focused on the pharmacogenetics of IL-6.

DI RENZO, L., Bianchi, A., Saraceno, R., Calabrese, V., Cornelius, C., Iacopino, L., et al. (2012). -174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers. PHARMACOGENETICS AND GENOMICS, 22(2), 134-142 [10.1097/FPC.0b013e32834e5e7b].

-174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers

DI RENZO, LAURA;SARACENO, ROSITA;IACOPINO, LEONARDO;CHIMENTI, SERGIO;DE LORENZO, ANTONINO
2012

Abstract

Although TNF-α blockade is a very effective therapy for psoriasis, not all patients achieve a favorable outcome. The association between IL-6 and psoriasis has been investigated but no papers have focused on the pharmacogenetics of IL-6.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/49 - Scienze Tecniche Dietetiche Applicate
Settore MED/35 - Malattie Cutanee e Veneree
English
Con Impact Factor ISI
Genotype; Tumor Necrosis Factor-alpha; Promoter Regions, Genetic; Psoriasis; Polymorphism, Genetic; Risk Factors; Humans; Adult; Absorptiometry, Photon; Interleukin-6; Body Mass Index; Male
DI RENZO, L., Bianchi, A., Saraceno, R., Calabrese, V., Cornelius, C., Iacopino, L., et al. (2012). -174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers. PHARMACOGENETICS AND GENOMICS, 22(2), 134-142 [10.1097/FPC.0b013e32834e5e7b].
DI RENZO, L; Bianchi, A; Saraceno, R; Calabrese, V; Cornelius, C; Iacopino, L; Chimenti, S; DE LORENZO, A
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
45 articolo-2012-PHARMACOGENETIC-GENOMICS PSO.pdf

non disponibili

Descrizione: articolo principale
Licenza: Copyright dell'editore
Dimensione 296.27 kB
Formato Adobe PDF
296.27 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/77937
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 41
  • ???jsp.display-item.citation.isi??? 42
social impact