During haemodialysis procedure, the contact of blood with the membrane material contained in the hemodialyser results in protein deposition and adsorption, and surface-adsorbed proteins may trigger a variety of biological pathways with potential pathophysiologic consequences. The present work was undertaken to examine for protein adsorption capacity of two membranes used for clinical haemodialysis, namely cellulose triacetate (a derivatized cellulosic membrane) and the synthetic polymer polysulfone-based helixone.
Urbani, A., Sirolli, V., Lupisella, S., Bernardini, S., Levi Mortera, S., Pavone, B., et al. (2012). Proteomic investigations on the effect of different membrane materials on blood protein adsorption during haemodialysis. BLOOD TRANSFUSION, 10(Suppl 2), 101-112 [10.2450/2012.014S].
Proteomic investigations on the effect of different membrane materials on blood protein adsorption during haemodialysis
URBANI, ANDREA;BERNARDINI, SERGIO;PIERONI, LUISA;
2012-05-01
Abstract
During haemodialysis procedure, the contact of blood with the membrane material contained in the hemodialyser results in protein deposition and adsorption, and surface-adsorbed proteins may trigger a variety of biological pathways with potential pathophysiologic consequences. The present work was undertaken to examine for protein adsorption capacity of two membranes used for clinical haemodialysis, namely cellulose triacetate (a derivatized cellulosic membrane) and the synthetic polymer polysulfone-based helixone.| File | Dimensione | Formato | |
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