HIV RNA monitoring is not available in most antiretroviral treatment (ART) programs in sub-Saharan Africa; switch to second-line therapy is mostly guided by clinical/immunological criteria. This may lead to unnecessary disease progression and drug resistance accumulation. We investigated the prognostic value of virological and immunological status 6 months after ART initiation with respect to death, loss to follow-up, and treatment switch.
De Luca, A., Marazzi, M., Mancinelli, S., Ceffa, S., DORO ALTAN, A.m., Buonomo, E., et al. (2012). Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 59(3), 236-244 [10.1097/QAI.0b013e31824276e9].
Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa
MANCINELLI, SANDRO;DORO ALTAN, ANNA MARIA;BUONOMO, ERSILIA;SCARCELLA, PAOLA;LIOTTA, GIUSEPPE;PALOMBI, LEONARDO
2012-03-01
Abstract
HIV RNA monitoring is not available in most antiretroviral treatment (ART) programs in sub-Saharan Africa; switch to second-line therapy is mostly guided by clinical/immunological criteria. This may lead to unnecessary disease progression and drug resistance accumulation. We investigated the prognostic value of virological and immunological status 6 months after ART initiation with respect to death, loss to follow-up, and treatment switch.| File | Dimensione | Formato | |
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