The airway surface liquid (ASL) of Cystic Fibrosis (CF) patients contains a lower concentration of reduced glutathione (GSH) with respect to healthy people. It is not known whether this defect may favor lung colonization by opportunistic pathogens.

D'Orazio, M., Pacello, F., Battistoni, A. (2012). Extracellular glutathione decreases the ability of Burkholderia cenocepacia to penetrate into epithelial cells and to induce an inflammatory response. PLOS ONE, 7(10), e47550-e47550 [10.1371/journal.pone.0047550].

Extracellular glutathione decreases the ability of Burkholderia cenocepacia to penetrate into epithelial cells and to induce an inflammatory response

D'Orazio M;Pacello F;Battistoni A
2012-01-01

Abstract

The airway surface liquid (ASL) of Cystic Fibrosis (CF) patients contains a lower concentration of reduced glutathione (GSH) with respect to healthy people. It is not known whether this defect may favor lung colonization by opportunistic pathogens.
2012
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10 - BIOCHIMICA
English
Con Impact Factor ISI
respiratory mucosa; tumor necrosis factor-alpha; glutathione; humans; primary cell culture; interleukin-1beta; burkholderia infections; host-pathogen interactions; inflammation; oxidation-reduction; bronchi; cystic fibrosis; epithelial cells; burkholderia cenocepacia; Interleukin-8; Trachea; Cell Line
D'Orazio, M., Pacello, F., Battistoni, A. (2012). Extracellular glutathione decreases the ability of Burkholderia cenocepacia to penetrate into epithelial cells and to induce an inflammatory response. PLOS ONE, 7(10), e47550-e47550 [10.1371/journal.pone.0047550].
D'Orazio, M; Pacello, F; Battistoni, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/76168
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