Influence of external electric field as well as base substitution effects on the reduction/oxidation free energies of single stranded DNA suggest that base sequencing via measuring redox properties might be feasible under the conditions that (i) a difference of similar to 230 kJ mol(-1) in the oxidation potentials is enough to discriminate between nucleobases conductance signals and (ii) the strand is long enough to reduce end effects.
D'Abramo, M., Orozco, M., Amadei, A. (2011). Effects of local electric fields on the redox free energy of single stranded DNA. CHEMICAL COMMUNICATIONS, 47(9), 2646-2648 [10.1039/c0cc04352d].
Effects of local electric fields on the redox free energy of single stranded DNA
AMADEI, ANDREA
2011-01-01
Abstract
Influence of external electric field as well as base substitution effects on the reduction/oxidation free energies of single stranded DNA suggest that base sequencing via measuring redox properties might be feasible under the conditions that (i) a difference of similar to 230 kJ mol(-1) in the oxidation potentials is enough to discriminate between nucleobases conductance signals and (ii) the strand is long enough to reduce end effects.File in questo prodotto:
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