The identification of novel reverse-transcriptase (RT) drug-resistance mutations is critical in predicting the probability of success to anti-HBV treatment. Furthermore, due to HBV-RT/HBsAg gene-overlap, they can have an impact on HBsAg-detection and quantification.

Cento, V., Van Hemert, F., Neumann Fraune, M., Mirabelli, C., Di Maio, V., Salpini, R., et al. (2013). Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen. JOURNAL OF INFECTION, 67(4), 303-312 [10.1016/j.jinf.2013.05.008].

Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen

Salpini, R;BERTOLI, ADA;SARRECCHIA, CESARE;CECCHERINI SILBERSTEIN, FRANCESCA;ANDREONI, MASSIMO;ANGELICO, MARIO;SVICHER, VALENTINA
2013-06-22

Abstract

The identification of novel reverse-transcriptase (RT) drug-resistance mutations is critical in predicting the probability of success to anti-HBV treatment. Furthermore, due to HBV-RT/HBsAg gene-overlap, they can have an impact on HBsAg-detection and quantification.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/07 - Microbiologia e Microbiologia Clinica
Settore MED/17 - Malattie Infettive
English
Con Impact Factor ISI
HBsAg structure; HBsAg stop codon; HBsAg secretion; Treatment failure; HBV drug-resistance
Cento, V., Van Hemert, F., Neumann Fraune, M., Mirabelli, C., Di Maio, V., Salpini, R., et al. (2013). Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen. JOURNAL OF INFECTION, 67(4), 303-312 [10.1016/j.jinf.2013.05.008].
Cento, V; Van Hemert, F; Neumann Fraune, M; Mirabelli, C; Di Maio, V; Salpini, R; Bertoli, A; Micheli, V; Gubertini, G; Romano, S; Visca, M; De Sanctis, G; Berkhout, B; Marino, N; Mazzotta, F; Cappiello, G; Spanò, A; Sarrecchia, C; CECCHERINI SILBERSTEIN, F; Andreoni, M; Angelico, M; Verheyen, J; Perno, Cf; Svicher, V
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/75669
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