The false-positive rate (FPR) is a percentage-score provided by Geno2Pheno-algorithm indicating the likelihood that a V3-sequence is falsely predicted as CXCR4-using. We evaluated the correlation between FPR obtained by V3 population-sequencing and the burden of CXCR4-using variants detected by V3 ultra-deep sequencing (UDPS) and Enhanced-Sensitivity Trofile assay (ESTA).
Svicher, V., Cento, V., Rozera, G., Abbate, I., Santoro, M., Armenia, D., et al. (2013). The genotypic false positive rate determined by V3 population sequencing can predict the burden of HIV-1 CXCR4-using species detected by pyrosequencing. PLOS ONE, 8(1) [10.1371/journal.pone.0053603].
The genotypic false positive rate determined by V3 population sequencing can predict the burden of HIV-1 CXCR4-using species detected by pyrosequencing
SVICHER, VALENTINA;SANTORO, MARIA;ANDREONI, MASSIMO;CECCHERINI SILBERSTEIN, FRANCESCA;PERNO, CARLO FEDERICO
2013-01-01
Abstract
The false-positive rate (FPR) is a percentage-score provided by Geno2Pheno-algorithm indicating the likelihood that a V3-sequence is falsely predicted as CXCR4-using. We evaluated the correlation between FPR obtained by V3 population-sequencing and the burden of CXCR4-using variants detected by V3 ultra-deep sequencing (UDPS) and Enhanced-Sensitivity Trofile assay (ESTA).| File | Dimensione | Formato | |
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