Human arterial biopsies were studied by morphometrical, cytochemical, autoradiographic and ultrastructural methods with the aim of determining whether intimal lesions in atherosclerosis are characterized by definite cytological patterns. The results have shown: 1. a strong association between fibro-atheromatous plaques and foam and monocyte-like cells; 2. very few foam cells in diffuse intimal thickening and pearly-white fibrous plaques; 3. macrophages and foam cells were the only cytotypes consistently labelled with 3H-TdR and presumably proliferating in the fibro-atheromatous plaques.

Spagnoli, L.g., Villaschi, S., Palmieri, G., Mauriello, A. (1984). Foam cells in the development of human atheroma: a morphological and autoradiographic approach. WIENER KLINISCHE WOCHENSCHRIFT, 96(11), 412-418.

Foam cells in the development of human atheroma: a morphological and autoradiographic approach

SPAGNOLI, LUIGI GIUSTO;VILLASCHI, SERGIO;PALMIERI, GIAMPIERO;MAURIELLO, ALESSANDRO
1984-05-25

Abstract

Human arterial biopsies were studied by morphometrical, cytochemical, autoradiographic and ultrastructural methods with the aim of determining whether intimal lesions in atherosclerosis are characterized by definite cytological patterns. The results have shown: 1. a strong association between fibro-atheromatous plaques and foam and monocyte-like cells; 2. very few foam cells in diffuse intimal thickening and pearly-white fibrous plaques; 3. macrophages and foam cells were the only cytotypes consistently labelled with 3H-TdR and presumably proliferating in the fibro-atheromatous plaques.
25-mag-1984
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/08 - ANATOMIA PATOLOGICA
English
Macrophages; Tritium; Humans; Foam Cells; Arteriosclerosis; Autoradiography; Thymidine; Male; Female; Naphthol AS D Esterase
Spagnoli, L.g., Villaschi, S., Palmieri, G., Mauriello, A. (1984). Foam cells in the development of human atheroma: a morphological and autoradiographic approach. WIENER KLINISCHE WOCHENSCHRIFT, 96(11), 412-418.
Spagnoli, Lg; Villaschi, S; Palmieri, G; Mauriello, A
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/69369
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