Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, accuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 1973. A patient with a 3-month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed.

Bianchi, L., Orlandi, A., Iraci, S., Spagnoli, L.g., Nini, G. (1994). Punctate porokeratotic keratoderma--its occurrence with internal neoplasia. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 19(2), 139-141.

Punctate porokeratotic keratoderma--its occurrence with internal neoplasia

BIANCHI, LUCA;ORLANDI, AUGUSTO;SPAGNOLI, LUIGI GIUSTO;NINI, GABRIELE
1994-03-01

Abstract

Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, accuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 1973. A patient with a 3-month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed.
mar-1994
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/08 - ANATOMIA PATOLOGICA
English
Con Impact Factor ISI
Skin; Porokeratosis; Humans; Keratoderma, Palmoplantar; Middle Aged; Bronchial Neoplasms; Male
Bianchi, L., Orlandi, A., Iraci, S., Spagnoli, L.g., Nini, G. (1994). Punctate porokeratotic keratoderma--its occurrence with internal neoplasia. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 19(2), 139-141.
Bianchi, L; Orlandi, A; Iraci, S; Spagnoli, Lg; Nini, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/69311
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