The experience of 13 bone marrow processings is reported: 7 patients were affected by Acute Leukemias, 4 by Non Hodgkin's Lymphomas, 1 by Chronic Myelogenous Leukemia in complete remission after induction chemotherapy, 1 by Ewing's Sarcoma. Gravity sedimentation technique with 6% hydroxyethyl starch was used in all cases. A mean value of 0.754 x 10(8)/kg body weight mononuclear cells was harvested after sedimentation, with a mean recovery of 74.554%. Mean CFU-GM value was 0.543 x 10(4)/kg body weight. Only one evaluable patient, affected by ANLL, underwent Autologous Bone Marrow Transplantation and a full engraftment was noted on day +14. Results are discussed and further studies are proposed to clarify the relationship between the in vitro CFU-GM growth and the bone marrow engraftment.

Adorno, G., Tribalto, M., Cantonetti, M., di Toritto, T., Cudillo, L., Dentamaro, T., et al. (1990). Bone marrow processing with a gravity sedimentation technique: experience of 13 cases. HAEMATOLOGICA, 75(supplemento 1), 48-50.

Bone marrow processing with a gravity sedimentation technique: experience of 13 cases

ADORNO, GASPARE;TRIBALTO, MAURIZIO;CANTONETTI, MARIA;CUDILLO, LAURA;
1990-01-01

Abstract

The experience of 13 bone marrow processings is reported: 7 patients were affected by Acute Leukemias, 4 by Non Hodgkin's Lymphomas, 1 by Chronic Myelogenous Leukemia in complete remission after induction chemotherapy, 1 by Ewing's Sarcoma. Gravity sedimentation technique with 6% hydroxyethyl starch was used in all cases. A mean value of 0.754 x 10(8)/kg body weight mononuclear cells was harvested after sedimentation, with a mean recovery of 74.554%. Mean CFU-GM value was 0.543 x 10(4)/kg body weight. Only one evaluable patient, affected by ANLL, underwent Autologous Bone Marrow Transplantation and a full engraftment was noted on day +14. Results are discussed and further studies are proposed to clarify the relationship between the in vitro CFU-GM growth and the bone marrow engraftment.
1990
Pubblicato
Rilevanza internazionale
Lettera
Sì, ma tipo non specificato
Settore MED/15 - MALATTIE DEL SANGUE
Settore MED/06 - ONCOLOGIA MEDICA
English
Con Impact Factor ISI
Bone Marrow Cells; Humans; Adult; Specimen Handling; Retrospective Studies; Middle Aged; Hetastarch; Adolescent; Male; Female; Bone Marrow Transplantation
Adorno, G., Tribalto, M., Cantonetti, M., di Toritto, T., Cudillo, L., Dentamaro, T., et al. (1990). Bone marrow processing with a gravity sedimentation technique: experience of 13 cases. HAEMATOLOGICA, 75(supplemento 1), 48-50.
Adorno, G; Tribalto, M; Cantonetti, M; di Toritto, T; Cudillo, L; Dentamaro, T; Iampieri, M; Lucanto, E; Masi, M; Riguzzi, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/69192
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