Ten consecutive children with high risk leukemia have been submitted to UCB transplant from unrelated HLA mismatched donors. All patients received an identical regimen for conditioning and GVHD prophylaxis. The median dose of viable nucleated cells infused was 2.6 x 10(6)/kg b.w. Among the nine patients evaluable for engraftment the hematopoiesis was of full donor origin in six patients and autologous in three. At a median follow-up of 9 months, six of nine (67%) patients are alive in CR.

Iori, A., Screnci, M., Guglielmi, C., Mengarelli, A., Carmini, D., Testi, A., et al. (1998). Umbilical cord blood (UCB) transplant from unrelated mismatched donor in patients with high risk (HR) leukemia. BONE MARROW TRANSPLANTATION, 22 Suppl 1, S75-S75.

Umbilical cord blood (UCB) transplant from unrelated mismatched donor in patients with high risk (HR) leukemia

ROMANO, ANDREA;ARCESE, WILLIAM
1998-07-01

Abstract

Ten consecutive children with high risk leukemia have been submitted to UCB transplant from unrelated HLA mismatched donors. All patients received an identical regimen for conditioning and GVHD prophylaxis. The median dose of viable nucleated cells infused was 2.6 x 10(6)/kg b.w. Among the nine patients evaluable for engraftment the hematopoiesis was of full donor origin in six patients and autologous in three. At a median follow-up of 9 months, six of nine (67%) patients are alive in CR.
lug-1998
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Con Impact Factor ISI
Transplantation Conditioning; Hematopoietic Stem Cells; Humans; Child; Hematopoiesis; Child, Preschool; Leukemia; Histocompatibility Testing; Risk Factors; Fetal Blood; Treatment Outcome; Hematopoietic Stem Cell Transplantation; Graft vs Host Disease; Adolescent; Female; Male
Iori, A., Screnci, M., Guglielmi, C., Mengarelli, A., Carmini, D., Testi, A., et al. (1998). Umbilical cord blood (UCB) transplant from unrelated mismatched donor in patients with high risk (HR) leukemia. BONE MARROW TRANSPLANTATION, 22 Suppl 1, S75-S75.
Iori, A; Screnci, M; Guglielmi, C; Mengarelli, A; Carmini, D; Testi, A; Moleti, M; Cimino, G; Perrone, P; Laurenti, L; Elia, L; Boecklin, F; Romano, A; Vulcano, F; De Felice, L; Arcese, W
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/68980
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