From this retrospective single center analysis adults with acute lymphoblastic leukemia transplanted in > or 2nd CR from an HLA-identical sibling later than 1993 had a worse outcome. As the transplanted-related mortality improved by time,this result was essentially due to the increased relapse rate. The intensity of the pre-transplant salvage chemotherapy was identified as the main factor influencing the post-transplant relapse-risk.

Mengarelli, A., Iori, A., Cerretti, R., Cerilli, L., Romano, A., Arcese, W. (2002). Increasing risk of relapse after allogeneic stem cell transplant for adult acute lymphoblastic leukemia in > or = 2nd complete remission induced by highly intensive chemotherapy. HAEMATOLOGICA, 87(7), 782-784.

Increasing risk of relapse after allogeneic stem cell transplant for adult acute lymphoblastic leukemia in > or = 2nd complete remission induced by highly intensive chemotherapy

ROMANO, ANDREA;ARCESE, WILLIAM
2002-07-01

Abstract

From this retrospective single center analysis adults with acute lymphoblastic leukemia transplanted in > or 2nd CR from an HLA-identical sibling later than 1993 had a worse outcome. As the transplanted-related mortality improved by time,this result was essentially due to the increased relapse rate. The intensity of the pre-transplant salvage chemotherapy was identified as the main factor influencing the post-transplant relapse-risk.
lug-2002
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Con Impact Factor ISI
Precursor Cell Lymphoblastic Leukemia-Lymphoma; Humans; Retrospective Studies; Transplantation, Homologous; Recurrence; Drug Resistance, Multiple; Risk; Adult; Antineoplastic Combined Chemotherapy Protocols; Adolescent; Stem Cell Transplantation; Female; Male; Remission Induction
Mengarelli, A., Iori, A., Cerretti, R., Cerilli, L., Romano, A., Arcese, W. (2002). Increasing risk of relapse after allogeneic stem cell transplant for adult acute lymphoblastic leukemia in > or = 2nd complete remission induced by highly intensive chemotherapy. HAEMATOLOGICA, 87(7), 782-784.
Mengarelli, A; Iori, A; Cerretti, R; Cerilli, L; Romano, A; Arcese, W
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/68295
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