Nasal polyps (NPs) are abnormal lesions that arise from any portion of the nasal mucosa or paranasal sinuses within the nasal cavities. They are characterized by the formation of inflammatory swellings of unstable respiratory mucosa, which protrude into the nasal cavity. The causes and the pathogenesis of NP development are not well understood. The current and principal hypothesis is that NPs result from allergy and inflammation, which cause an unstable respiratory mucosa with increased epithelial cell proliferation and epithelial morphologic changes.
Corradini, C., Gullotta, F., Ciacci, S., Palmieri, G., Salehi, L., De Corso, E., et al. (2008). Hyperproliferation in nasal polyposis tissues is not associated with somatic genomic instability. JOURNAL OF OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 37(4), 510-514 [10.2310/7070.2008.0097].
Hyperproliferation in nasal polyposis tissues is not associated with somatic genomic instability
PALMIERI, GIAMPIERO;NOVELLI, GIUSEPPE;GAMBARDELLA, SERGIO
2008-08-01
Abstract
Nasal polyps (NPs) are abnormal lesions that arise from any portion of the nasal mucosa or paranasal sinuses within the nasal cavities. They are characterized by the formation of inflammatory swellings of unstable respiratory mucosa, which protrude into the nasal cavity. The causes and the pathogenesis of NP development are not well understood. The current and principal hypothesis is that NPs result from allergy and inflammation, which cause an unstable respiratory mucosa with increased epithelial cell proliferation and epithelial morphologic changes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
