The aim of the present study was to evaluate the efficacy of an oral specific hyposensitization therapy in children with atopic dermatitis and positive prick skin tests and/or RAST to Dermatophagoides pteronyssinus (D.pt.). A total of 60 patients, in three different clinical groups, were selected for a three years clinical trial. Group A: children with atopic dermatitis and allergic asthma and/or rhinitis; groups B and C: children with exclusively atopic dermatitis. Groups A and B received specific hyposensitization therapy. Group C was the control group. The clinical evaluation of the dermatological lesions, at the end of our study, didn't show any significant difference among the three groups. Moreover, the onset of respiratory symptoms between the two groups with exclusively atopic dermatitis was similar and not related to the positivity of prick skin tests and/or RAST to seasonal allergens. Our study suggests that specific hyposensitisation therapy with extracts of D.pt., although with no side effects, does not affect the natural history of atopic dermatitis.

Galli, E., Chini, L., Nardi, S., Benincori, N., Panei, P., Fraioli, G., et al. (1994). Use of a specific oral hyposensitization therapy to Dermatophagoides pteronyssinus in children with atopic dermatitis. ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 22(1), 18-22.

Use of a specific oral hyposensitization therapy to Dermatophagoides pteronyssinus in children with atopic dermatitis

CHINI, LOREDANA;MOSCHESE, VIVIANA;ROSSI, PAOLO
1994-01-01

Abstract

The aim of the present study was to evaluate the efficacy of an oral specific hyposensitization therapy in children with atopic dermatitis and positive prick skin tests and/or RAST to Dermatophagoides pteronyssinus (D.pt.). A total of 60 patients, in three different clinical groups, were selected for a three years clinical trial. Group A: children with atopic dermatitis and allergic asthma and/or rhinitis; groups B and C: children with exclusively atopic dermatitis. Groups A and B received specific hyposensitization therapy. Group C was the control group. The clinical evaluation of the dermatological lesions, at the end of our study, didn't show any significant difference among the three groups. Moreover, the onset of respiratory symptoms between the two groups with exclusively atopic dermatitis was similar and not related to the positivity of prick skin tests and/or RAST to seasonal allergens. Our study suggests that specific hyposensitisation therapy with extracts of D.pt., although with no side effects, does not affect the natural history of atopic dermatitis.
1994
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
English
Con Impact Factor ISI
Administration, Oral; Animals; Intradermal Tests; Dermatitis, Atopic; Antigens, Dermatophagoides; Combined Modality Therapy; Humans; Desensitization, Immunologic; Child; Child, Preschool; Infant; Immunoglobulin E; Treatment Outcome; Mites; Follow-Up Studies; Glycoproteins; Male; Female; Respiratory Hypersensitivity
Galli, E., Chini, L., Nardi, S., Benincori, N., Panei, P., Fraioli, G., et al. (1994). Use of a specific oral hyposensitization therapy to Dermatophagoides pteronyssinus in children with atopic dermatitis. ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 22(1), 18-22.
Galli, E; Chini, L; Nardi, S; Benincori, N; Panei, P; Fraioli, G; Moschese, V; Rossi, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/66970
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