Aortic valve disease is presently the number one indication for valve replacement in the United States, yet its molecular mechanisms remain unknown. As apoptosis (programmed cell death) occurs in degenerative disease states, it was postulated that experimental hypercholesterolemia is associated with apoptosis in rabbit aortic valves.
Rajamannan, N., Sangiorgi, G., Springett, M., Arnold, K., Mohacsi, T., Spagnoli, L.g., et al. (2001). Experimental hypercholesterolemia induces apoptosis in the aortic valve. JOURNAL OF HEART VALVE DISEASE, 10(3), 371-374.
Experimental hypercholesterolemia induces apoptosis in the aortic valve
SANGIORGI, GIUSEPPE;SPAGNOLI, LUIGI GIUSTO;
2001-05-01
Abstract
Aortic valve disease is presently the number one indication for valve replacement in the United States, yet its molecular mechanisms remain unknown. As apoptosis (programmed cell death) occurs in degenerative disease states, it was postulated that experimental hypercholesterolemia is associated with apoptosis in rabbit aortic valves.File in questo prodotto:
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2001-11380101-JHVD-Exper Hypercol AoV Apoptosis.pdf
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