Epidemiological studies have demonstrated that hyperfibrinogenemia is an independent risk factor for cerebrovascular atherosclerosis. However, the underlying mechanisms are poorly understood. We studied whether hyperfibrinogenemia could modify the histological composition of atherosclerotic plaque and precipitate carotid thrombosis resulting from rupture of the plaque.

Mauriello, A., Sangiorgi, G., Palmieri, G., Virmani, R., Holmes, D., Schwartz, R., et al. (2000). Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks. CIRCULATION, 101(7), 744-750.

Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks

MAURIELLO, ALESSANDRO;PALMIERI, GIAMPIERO;IPPOLITI, ARNALDO;SPAGNOLI, LUIGI GIUSTO
2000-02-22

Abstract

Epidemiological studies have demonstrated that hyperfibrinogenemia is an independent risk factor for cerebrovascular atherosclerosis. However, the underlying mechanisms are poorly understood. We studied whether hyperfibrinogenemia could modify the histological composition of atherosclerotic plaque and precipitate carotid thrombosis resulting from rupture of the plaque.
22-feb-2000
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/08 - ANATOMIA PATOLOGICA
English
Ischemic Attack, Transient; Intracranial Thrombosis; Risk Factors; Humans; Fibrinogen; Aged; Middle Aged; Arteriosclerosis; Carotid Artery Diseases; Male; Female; Multivariate Analysis
Mauriello, A., Sangiorgi, G., Palmieri, G., Virmani, R., Holmes, D., Schwartz, R., et al. (2000). Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks. CIRCULATION, 101(7), 744-750.
Mauriello, A; Sangiorgi, G; Palmieri, G; Virmani, R; Holmes, D; Schwartz, R; Pistolese, R; Ippoliti, A; Spagnoli, Lg
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/66753
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 89
  • ???jsp.display-item.citation.isi??? 72
social impact