Recent studies suggest a complex association between smoking and retinopathy that probably depends on the interaction between many variables. We have reported an association between ACP1 phenotype and retinopathy in type 1 diabetes. Additionally, the deleterious effects of smoking on intrauterine growth are dependent on ACP1, a low-molecular-weight tyrosine phosphatase that modifies signal transduction. We examine here the interaction between smoking and ACP1 as a mediator of susceptibility to diabetic retinopathy in a sample of puerperae with type 1 diabetes.
Magrini, A., Bottini, N., Nicotra, M., Cosmi, E., Bottini, E., Bergamaschi, A. (2002). Smoking and the genetics of signal transduction: an association study on retinopathy in type 1 diabetes. THE AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 324(6), 310-313.
Smoking and the genetics of signal transduction: an association study on retinopathy in type 1 diabetes
MAGRINI, ANDREA;BOTTINI, NUNZIO;BOTTINI, EGIDIO;BERGAMASCHI, ANTONIO
2002-12-01
Abstract
Recent studies suggest a complex association between smoking and retinopathy that probably depends on the interaction between many variables. We have reported an association between ACP1 phenotype and retinopathy in type 1 diabetes. Additionally, the deleterious effects of smoking on intrauterine growth are dependent on ACP1, a low-molecular-weight tyrosine phosphatase that modifies signal transduction. We examine here the interaction between smoking and ACP1 as a mediator of susceptibility to diabetic retinopathy in a sample of puerperae with type 1 diabetes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
