The involvement of lipid components in hepatitis A virus (HAV) attachment to host cells has been investigated. Isolated Frp/3 cell membranes and whole lipids, phospholipid and glycolipid fractions extracted from them were able to bind the virus and to prevent infection. Treatment of virus with various phospholipids or glycolipids demonstrated the participation of phosphatidylserine, phosphatidylethanolamine and galactose in HAV binding. Results obtained added further information on the receptor specificity of host cells for HAV.

Seganti, L., Superti, F., Orsi, N., Gabrieli, R., Divizia, M., Pana', A. (1989). Membrane lipid components interacting with hepatitis A virus. MICROBIOLOGICA, 12(3), 225-230.

Membrane lipid components interacting with hepatitis A virus

GABRIELI, ROSANNA;DIVIZIA, MAURIZIO;PANA', AUGUSTO
1989-07-01

Abstract

The involvement of lipid components in hepatitis A virus (HAV) attachment to host cells has been investigated. Isolated Frp/3 cell membranes and whole lipids, phospholipid and glycolipid fractions extracted from them were able to bind the virus and to prevent infection. Treatment of virus with various phospholipids or glycolipids demonstrated the participation of phosphatidylserine, phosphatidylethanolamine and galactose in HAV binding. Results obtained added further information on the receptor specificity of host cells for HAV.
lug-1989
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/42 - IGIENE GENERALE E APPLICATA
English
Animals; Membrane Lipids; Binding, Competitive; Hepatovirus; Cell Membrane; Cell Line; Cell Adhesion
Seganti, L., Superti, F., Orsi, N., Gabrieli, R., Divizia, M., Pana', A. (1989). Membrane lipid components interacting with hepatitis A virus. MICROBIOLOGICA, 12(3), 225-230.
Seganti, L; Superti, F; Orsi, N; Gabrieli, R; Divizia, M; Pana', A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/66659
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