Research has been carried out in order to clarify the chemical nature of cell receptors interacting with a fast growing strain of hepatitis A virus (HAV) producing a cytopathic effect on Frp/3 cells. Cell surface susceptibility to HAV attachment has been studied after treatment with enzymes acting on different chemical groupings. Results obtained showed a lowering of cell susceptibility to HAV infection following the action of phospholipase A2, phospholipase C, trypsin and beta-galactosidase. These data suggested that phospholipids, proteins and galactose participate to the cellular receptorial area for HAV.
Seganti, L., Superti, F., Orsi, N., Gabrieli, R., Divizia, M., Panà, A. (1987). Study of the chemical nature of Frp/3 cell recognition units for hepatitis A virus. MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 176(1), 21-26.
Study of the chemical nature of Frp/3 cell recognition units for hepatitis A virus
GABRIELI, ROSANNA;DIVIZIA, MAURIZIO;
1987-01-01
Abstract
Research has been carried out in order to clarify the chemical nature of cell receptors interacting with a fast growing strain of hepatitis A virus (HAV) producing a cytopathic effect on Frp/3 cells. Cell surface susceptibility to HAV attachment has been studied after treatment with enzymes acting on different chemical groupings. Results obtained showed a lowering of cell susceptibility to HAV infection following the action of phospholipase A2, phospholipase C, trypsin and beta-galactosidase. These data suggested that phospholipids, proteins and galactose participate to the cellular receptorial area for HAV.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.