Adult pairs of Schistosoma mansoni were kept in culture in the presence or absence of various bile salts and the numbers of parasite eggs deposited in vitro were monitored for 2 weeks. The hydrophilic bile salt tauroursodeoxycholic acid (TUDCA) was found to produce a highly significant increase in the number of eggs deposited during the 1st week of culture. The hydrophobic bile salt taurochenodeoxycholic acid (TCDCA) and the intermediately hydrophobic salt taurocholate (TCA) produced more moderate increases. These results expand previous data showing that schistosomes kept in the presence of portal blood have higher oviposition rates than schistosomes kept in systemic blood.
Badr, S., Pica Mattoccia, L., Moroni, R., Angelico, M., Cioli, D. (1999). Effect of bile salts on oviposition in vitro by Schistosoma mansoni. PARASITOLOGY RESEARCH, 85(5), 421-423.
Effect of bile salts on oviposition in vitro by Schistosoma mansoni
ANGELICO, MARIO;
1999-05-01
Abstract
Adult pairs of Schistosoma mansoni were kept in culture in the presence or absence of various bile salts and the numbers of parasite eggs deposited in vitro were monitored for 2 weeks. The hydrophilic bile salt tauroursodeoxycholic acid (TUDCA) was found to produce a highly significant increase in the number of eggs deposited during the 1st week of culture. The hydrophobic bile salt taurochenodeoxycholic acid (TCDCA) and the intermediately hydrophobic salt taurocholate (TCA) produced more moderate increases. These results expand previous data showing that schistosomes kept in the presence of portal blood have higher oviposition rates than schistosomes kept in systemic blood.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
