The expression of the mRNA for SLF (the c-kit ligand), a product of the "steel" locus, has been investigated in postnatal mouse testis and homogeneous populations of testicular cells. The message was found expressed in postnatal mouse testis but not in germ cells. Studies on primary mouse Sertoli cell cultures from 18 day old mice show that Sertoli cells are the site of SLF mRNA expression in the seminiferous tubules. Treatment of Sertoli cell cultures with cAMP analogs led to a significant increase in the SLF mRNA levels.

Rossi, P., Albanesi, C., Grimaldi, P., Geremia, R. (1991). Expression of the mRNA for the ligand of c-kit in mouse Sertoli cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 176(2), 910-914 [10.1016/S0006-291X(05)80272-4].

Expression of the mRNA for the ligand of c-kit in mouse Sertoli cells

ROSSI, PELLEGRINO;GRIMALDI, PAOLA;GEREMIA, RAFFAELE
1991-04-30

Abstract

The expression of the mRNA for SLF (the c-kit ligand), a product of the "steel" locus, has been investigated in postnatal mouse testis and homogeneous populations of testicular cells. The message was found expressed in postnatal mouse testis but not in germ cells. Studies on primary mouse Sertoli cell cultures from 18 day old mice show that Sertoli cells are the site of SLF mRNA expression in the seminiferous tubules. Treatment of Sertoli cell cultures with cAMP analogs led to a significant increase in the SLF mRNA levels.
30-apr-1991
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/16 - ANATOMIA UMANA
English
Con Impact Factor ISI
Animals; Testis; Proto-Oncogene Proteins c-kit; Cyclic AMP; Gene Expression; Protein-Tyrosine Kinases; Mice; RNA, Messenger; Mice, Inbred Strains; Proto-Oncogene Proteins; Sertoli Cells; Cells, Cultured; Ligands; Male
Rossi, P., Albanesi, C., Grimaldi, P., Geremia, R. (1991). Expression of the mRNA for the ligand of c-kit in mouse Sertoli cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 176(2), 910-914 [10.1016/S0006-291X(05)80272-4].
Rossi, P; Albanesi, C; Grimaldi, P; Geremia, R
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/65821
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