The expression of the mRNA for SLF (the c-kit ligand), a product of the "steel" locus, has been investigated in postnatal mouse testis and homogeneous populations of testicular cells. The message was found expressed in postnatal mouse testis but not in germ cells. Studies on primary mouse Sertoli cell cultures from 18 day old mice show that Sertoli cells are the site of SLF mRNA expression in the seminiferous tubules. Treatment of Sertoli cell cultures with cAMP analogs led to a significant increase in the SLF mRNA levels.
Rossi, P., Albanesi, C., Grimaldi, P., Geremia, R. (1991). Expression of the mRNA for the ligand of c-kit in mouse Sertoli cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 176(2), 910-914 [10.1016/S0006-291X(05)80272-4].
Expression of the mRNA for the ligand of c-kit in mouse Sertoli cells
ROSSI, PELLEGRINO;GRIMALDI, PAOLA;GEREMIA, RAFFAELE
1991-04-30
Abstract
The expression of the mRNA for SLF (the c-kit ligand), a product of the "steel" locus, has been investigated in postnatal mouse testis and homogeneous populations of testicular cells. The message was found expressed in postnatal mouse testis but not in germ cells. Studies on primary mouse Sertoli cell cultures from 18 day old mice show that Sertoli cells are the site of SLF mRNA expression in the seminiferous tubules. Treatment of Sertoli cell cultures with cAMP analogs led to a significant increase in the SLF mRNA levels.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
