The presence of surface-recognition mechanisms between somatic and germ cells of the seminiferous epithelium has been studied in the rat by an assay in vitro based on the ability of homogeneous populations of spermatogenic cells, at specific differentiative stages, to adhere to monolayers of cultured Sertoli cells. The results show that germ cells adhere specifically to Sertoli cells and that the adhesion is dependent on the differentiative stage of the germ cells. Pachytene spermatocytes show the highest ability to adhere and form typical junctional specializations with the underlying Sertoli cells, while round spermatids adhere much less to the substrate. The possible regulative role of a somatic cell-germ interaction is discussed.

Ziparo, E., Geremia, R., Russo, M.a., Stefanini, M. (1980). Surface interaction in vitro between Sertoli cells and germ cells at different stages of spermatogenesis. THE AMERICAN JOURNAL OF ANATOMY, 159(4), 385-388 [10.1002/aja.1001590404].

Surface interaction in vitro between Sertoli cells and germ cells at different stages of spermatogenesis

GEREMIA, RAFFAELE;RUSSO, MARIO ANTONIO;
1980-12-01

Abstract

The presence of surface-recognition mechanisms between somatic and germ cells of the seminiferous epithelium has been studied in the rat by an assay in vitro based on the ability of homogeneous populations of spermatogenic cells, at specific differentiative stages, to adhere to monolayers of cultured Sertoli cells. The results show that germ cells adhere specifically to Sertoli cells and that the adhesion is dependent on the differentiative stage of the germ cells. Pachytene spermatocytes show the highest ability to adhere and form typical junctional specializations with the underlying Sertoli cells, while round spermatids adhere much less to the substrate. The possible regulative role of a somatic cell-germ interaction is discussed.
dic-1980
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/19 - Microbiologia Generale
English
Con Impact Factor ISI
Seminiferous Epithelium; Rats; Animals; Sertoli Cells; Testis; Spermatozoa; Cell Differentiation; Cell Separation; Spermatogenesis; Male; Cell Adhesion
Ziparo, E., Geremia, R., Russo, M.a., Stefanini, M. (1980). Surface interaction in vitro between Sertoli cells and germ cells at different stages of spermatogenesis. THE AMERICAN JOURNAL OF ANATOMY, 159(4), 385-388 [10.1002/aja.1001590404].
Ziparo, E; Geremia, R; Russo, Ma; Stefanini, M
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/65647
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