Posttransplant diabetes mellitus (PTDM) has gained widespread attention due to the micro and macro-vascular complications that increase the morbidity and mortality of patients receiving solid organs. The higher incidence of PTDM has been mainly attributed to the immunosuppressive therapy. Therefore, this study compares the metabolic side effects of low dose maintenance therapy of FK-506 and Cyclosporin A (CsA) in 14 patients 1 year after orthotopic liver transplant and analyzes possible factors that contribute to the development of PTDM.

Fernandez, L., Lehmann, R., Luzi, L., Battezzati, A., Angelico, M., Ricordi, C., et al. (1999). The effects of maintenance doses of FK506 versus cyclosporin A on glucose and lipid metabolism after orthotopic liver transplantation. TRANSPLANTATION, 68(10), 1532-1541.

The effects of maintenance doses of FK506 versus cyclosporin A on glucose and lipid metabolism after orthotopic liver transplantation

ANGELICO, MARIO;
1999-11-27

Abstract

Posttransplant diabetes mellitus (PTDM) has gained widespread attention due to the micro and macro-vascular complications that increase the morbidity and mortality of patients receiving solid organs. The higher incidence of PTDM has been mainly attributed to the immunosuppressive therapy. Therefore, this study compares the metabolic side effects of low dose maintenance therapy of FK-506 and Cyclosporin A (CsA) in 14 patients 1 year after orthotopic liver transplant and analyzes possible factors that contribute to the development of PTDM.
27-nov-1999
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/12 - GASTROENTEROLOGIA
English
Con Impact Factor ISI
Cholesterol, HDL; Cyclosporine; Humans; Lipids; Diabetes Mellitus; Glucose; Tacrolimus; Energy Metabolism; Immunosuppressive Agents; Insulin; Liver Transplantation; Blood Glucose; Middle Aged; Female; Male
Fernandez, L., Lehmann, R., Luzi, L., Battezzati, A., Angelico, M., Ricordi, C., et al. (1999). The effects of maintenance doses of FK506 versus cyclosporin A on glucose and lipid metabolism after orthotopic liver transplantation. TRANSPLANTATION, 68(10), 1532-1541.
Fernandez, L; Lehmann, R; Luzi, L; Battezzati, A; Angelico, M; Ricordi, C; Tzakis, A; Alejandro, R
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/65570
Citazioni
  • ???jsp.display-item.citation.pmc??? 11
  • Scopus 79
  • ???jsp.display-item.citation.isi??? 71
social impact