Effetti della dietà sulla riduzione del rischio cardiovascolare

Background. Many epidemiological studies provide a clear evidence that hypercholesterolemia is associated with hypertension, cardiovascular disease risk. Consequently hypercholesterolemia should have treated with any cholesterol levels lowering agent in order to improve morbidity and mortality. Our objective was to assess the effect of diet on cardiovascular disease risk reduction. Patients and Methods. Our study group consisted of 33 obese patients, 15 women and 18 men means: age 45,91 ± 13,68 years, BMI 31,74 ± 6,34 kg/m2, and 16 Smokers, 16 sedentary e 17 hypertensive. We analysed anthropometric variables, body composition by Dual X-ray Absorptiometry, resting metabolic rate (RMR) by indirect calorimetry and bioumoral variables. Results. After the 6 (T1) and 12 months (T2) at baseline (T0), there was observed a significant decrease of fat , abdominal fat, LDL, TC , TG, and cardiovascular risk index (TG/HDL, LDL/HDL e CT/HDL). Lean, Resting Metabolic Rate and HDL did not show any statistical difference Conclusion. The results of ours study suggest that the diet and healthful lifestyle is associated with reduced cardiovascular disease risk.