EcoRI, RsaI, and MspI RFLPs of the COL1A2 gene were analyzed, using the polymerase chain reaction technique, for the first time in a native American population: the Cayapa of Ecuador. These polymorphisms recently turned out to be good anthropological markers, both at the allele and at the haplotype frequency level. These data underline the well-known genetic affinity between the Cayapa and Asian populations. Moreover, our data on DNA polymorphisms agree with the indication of extremely low, if any, gene flow into the Cayapa gene pool from the neighboring black community, as already suggested not only by cultural data but also by protein polymorphisms.

Pepe, G., Rickards, O., Bué, C., MARTINEZ-LABARGA, M.c., Tartaglia, M., De Stefano, G. (1994). EcoRI, RsaI, and MspI RFLPs of the COL1A2 gene (type I collagen) in the Cayapa, a Native American population of Ecuador. HUMAN BIOLOGY, 66(6), 979-989.

EcoRI, RsaI, and MspI RFLPs of the COL1A2 gene (type I collagen) in the Cayapa, a Native American population of Ecuador.

PEPE, GUGLIELMINA;RICKARDS, OLGA;MARTINEZ-LABARGA, MARIA CRISTINA;
1994-01-01

Abstract

EcoRI, RsaI, and MspI RFLPs of the COL1A2 gene were analyzed, using the polymerase chain reaction technique, for the first time in a native American population: the Cayapa of Ecuador. These polymorphisms recently turned out to be good anthropological markers, both at the allele and at the haplotype frequency level. These data underline the well-known genetic affinity between the Cayapa and Asian populations. Moreover, our data on DNA polymorphisms agree with the indication of extremely low, if any, gene flow into the Cayapa gene pool from the neighboring black community, as already suggested not only by cultural data but also by protein polymorphisms.
1994
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/08 - ANTROPOLOGIA
Settore BIO/18 - GENETICA
English
Con Impact Factor ISI
DNA markers, Native Americans
Pepe, G., Rickards, O., Bué, C., MARTINEZ-LABARGA, M.c., Tartaglia, M., De Stefano, G. (1994). EcoRI, RsaI, and MspI RFLPs of the COL1A2 gene (type I collagen) in the Cayapa, a Native American population of Ecuador. HUMAN BIOLOGY, 66(6), 979-989.
Pepe, G; Rickards, O; Bué, C; MARTINEZ-LABARGA, Mc; Tartaglia, M; De Stefano, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/64638
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