A report is presented about the capability of complement to directly clump Borrelia burgdorferi. The new phenomenon which has been termed ''microbial adherence'', is either antibody-independent or requires the presence of ''sensitizing'' antibodies depending the strains tested. Microbial adherence is associated with immobilization and killing of borrelias. A microbial adherence immobilization assay for B. burgdorferi (MAIA-BB) was developed to detect sensitizing antibodies in patients with Lyme borreliosis and in B. burgdorferi-infected animals.
Cacciapuoti, B., Ciceroni, L., Fontana, L., Perricone, R. (1993). Complement activation and sensitizing antibodies in lyme borreliosis - a microbial adherence immobilization assay for borrelia-burgdorferi (maia-bb). ZENTRALBLATT FUR BAKTERIOLOGIE, 278(1), 102-111.
Complement activation and sensitizing antibodies in lyme borreliosis - a microbial adherence immobilization assay for borrelia-burgdorferi (maia-bb)
FONTANA, LUIGI;PERRICONE, ROBERTO
1993-01-01
Abstract
A report is presented about the capability of complement to directly clump Borrelia burgdorferi. The new phenomenon which has been termed ''microbial adherence'', is either antibody-independent or requires the presence of ''sensitizing'' antibodies depending the strains tested. Microbial adherence is associated with immobilization and killing of borrelias. A microbial adherence immobilization assay for B. burgdorferi (MAIA-BB) was developed to detect sensitizing antibodies in patients with Lyme borreliosis and in B. burgdorferi-infected animals.Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons
