The improvement of Ewing sarcoma (EWS) therapy is currently linked to the discovery of strategies to select patients with poor and good prognosis and of modified treatment regimens. In this study, we analyzed the molecular factors governing EWS response to chemotherapy to identify genetic signatures to be used for risk-adapted therapy.

Scotlandi, K., Remondini, D., Castellani, G., Manara, M., Nardi, F., Cantiani, L., et al. (2009). Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome. JOURNAL OF CLINICAL ONCOLOGY, 27(13), 2209-16 [10.1200/JCO.2008.19.2542].

Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome

CACCURI, ANNA MARIA;
2009-05-01

Abstract

The improvement of Ewing sarcoma (EWS) therapy is currently linked to the discovery of strategies to select patients with poor and good prognosis and of modified treatment regimens. In this study, we analyzed the molecular factors governing EWS response to chemotherapy to identify genetic signatures to be used for risk-adapted therapy.
1-mag-2009
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10 - BIOCHIMICA
English
Male; Prognosis; Gene Expression Profiling; Female; Oxadiazoles; Principal Component Analysis; Humans; Cell Line, Tumor; Sarcoma, Ewing's; Antineoplastic Agents; Drug Resistance, Neoplasm; Glutathione S-Transferase pi; Glutathione Transferase; Bone Neoplasms
Scotlandi, K., Remondini, D., Castellani, G., Manara, M., Nardi, F., Cantiani, L., et al. (2009). Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome. JOURNAL OF CLINICAL ONCOLOGY, 27(13), 2209-16 [10.1200/JCO.2008.19.2542].
Scotlandi, K; Remondini, D; Castellani, G; Manara, M; Nardi, F; Cantiani, L; Francesconi, M; Mercuri, M; Caccuri, Am; Serra, M; Knuutila, S; Picci, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/64212
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