Pleural effusion is a common diagnostic problem and a challenge to the thoracic surgeon. The analysis of serum and body fluids for tumor markers is an established diagnostic procedure. Among various markers, tumors are linked to the overexpression of a glycolytic isoenzyme, M2-pyruvate-kinase (M2-PK). This preliminary study evaluated this enzyme as a tumor marker to differentiate malignant from benign pleural effusion.
Elia, S., Massoud, R., Guggino, G., Cristino, B., Cortese, C., De Massimi, A., et al. (2008). Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients: a further tool to define the need for invasive procedures. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 33(4), 723-727 [10.1016/j.ejcts.2008.01.014].
Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients: a further tool to define the need for invasive procedures
ELIA, STEFANO;MASSOUD, RENATO;CRISTINO, BENEDETTO;CORTESE, CLAUDIO;ZENOBI, ROSSELLA
2008-04-01
Abstract
Pleural effusion is a common diagnostic problem and a challenge to the thoracic surgeon. The analysis of serum and body fluids for tumor markers is an established diagnostic procedure. Among various markers, tumors are linked to the overexpression of a glycolytic isoenzyme, M2-pyruvate-kinase (M2-PK). This preliminary study evaluated this enzyme as a tumor marker to differentiate malignant from benign pleural effusion.| File | Dimensione | Formato | |
|---|---|---|---|
|
723_002.pdf
accesso aperto
Descrizione: articolo
Licenza:
Creative commons
Dimensione
155.48 kB
Formato
Adobe PDF
|
155.48 kB | Adobe PDF | Visualizza/Apri |
Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons
