In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.

Rossini, P., Zarola, F., Floris, R., Bernardi, G., Perretti, A., Pelosi, L., et al. (1989). Sensory (VEP, BAEP, SEP) and motor-evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis. EUROPEAN NEUROLOGY, 29(1), 41-47.

Sensory (VEP, BAEP, SEP) and motor-evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis

FLORIS, ROBERTO;BERNARDI, GIORGIO;
1989

Abstract

In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/36 - Diagnostica per Immagini e Radioterapia
English
Con Impact Factor ISI
adolescent; adult; auditory stimulation; central nervous system; cerebrospinal fluid; clinical article; computer analysis; diagnosis; evoked brain stem response; evoked muscle response; evoked somatosensory response; evoked visual response; female; human; immunology; isoelectric focusing; male; methodology; multiple sclerosis; nuclear magnetic resonance imaging; priority journal; Adolescent; Adult; Brain; Evoked Potentials; Female; Human; Immunoglobulins, gamma-Chain; Immunoglobulins, Heavy-Chain; Laterality; Magnetic Resonance Imaging; Male; Middle Age; Multiple Sclerosis
Rossini, P., Zarola, F., Floris, R., Bernardi, G., Perretti, A., Pelosi, L., et al. (1989). Sensory (VEP, BAEP, SEP) and motor-evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis. EUROPEAN NEUROLOGY, 29(1), 41-47.
Rossini, P; Zarola, F; Floris, R; Bernardi, G; Perretti, A; Pelosi, L; Caruso, G; Caramia, M
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/57398
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