Major depressive disorder (MDD) is associated with low-grade inflammation, and it is considered a risk factor for coronary artery disease (CAD). CD40 ligand (CD40L) plays an important role in inflammation, platelet activation, and clotting system activation. We investigated soluble CD40L (sCD40L) expression in MDD and assessed whether it may represent a molecular mechanism that links inflammation and a prothrombotic state and whether this condition may be modified by selective serotonin reuptake inhibitor (SSRI) therapy.
Leo, R., Di Lorenzo, G., Tesauro, M., Razzini, C., Forleo, G., Chiricolo, G., et al. (2006). Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy. JOURNAL OF CLINICAL PSYCHIATRY, 67(11), 1760-1766.
Tipologia: | Articolo su rivista |
Citazione: | Leo, R., Di Lorenzo, G., Tesauro, M., Razzini, C., Forleo, G., Chiricolo, G., et al. (2006). Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy. JOURNAL OF CLINICAL PSYCHIATRY, 67(11), 1760-1766. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/25 - Psichiatria |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | nov-2006 |
Titolo: | Association between enhanced soluble CD40 ligand and proinflammatory and prothrombotic states in major depressive disorder: pilot observations on the effects of selective serotonin reuptake inhibitor therapy |
Autori: | |
Autori: | Leo, R; Di Lorenzo, G; Tesauro, M; Razzini, C; Forleo, G; Chiricolo, G; Cola, C; Zanasi, M; Troisi, A; Siracusano, A; Lauro, R; Romeo, F |
Appare nelle tipologie: | 01 - Articolo su rivista |