Medical imaging has become of the utmost importance in evaluating patients with cancer. Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are accurate methods for detecting cancer and related metabolic abnormalities, but they often do not provide the anatomical landmarks needed to precisely localize lesions. Magnetic resonance imaging (MRI) and computed tomography (CT) scan, on the other hand, offer excellent anatomic detail but are less sensitive because they do not provide functional detail. Fusion imaging combines functional studies with morphological ones, so overcoming the drawbacks of both modalities. Software-based fusion of independently performed scintigraphic and radiological images has proven time consuming and impractical for routine use. Recently, dual-modality integrated imaging systems (SPECT/CT and PET/CT) have been developed: the acquired images are coregistered by means of the hardware in the same session. These new devices can be particularly useful for tumour imaging. The anatomical images provide precise localization and allow the exclusion of disease in sites of physiologic tracers' accumulation for SPECT and PET findings. Hybrid imaging in oncological applications has been very encouraging, indicating that these systems are suited for routine use in clinical practice. In fact, fused images provide additional information that improves diagnostic accuracy and impacts on patient management.

Schillaci, O., Simonetti, G. (2004). Fusion imaging in nuclear medicine - Applications of dual-modality systems in oncology. CANCER BIOTHERAPY & RADIOPHARMACEUTICALS, 19(1), 1-10 [10.1089/108497804773391621].

Fusion imaging in nuclear medicine - Applications of dual-modality systems in oncology

SCHILLACI, ORAZIO;SIMONETTI, GIOVANNI MARIA EGISTO
2004-01-01

Abstract

Medical imaging has become of the utmost importance in evaluating patients with cancer. Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are accurate methods for detecting cancer and related metabolic abnormalities, but they often do not provide the anatomical landmarks needed to precisely localize lesions. Magnetic resonance imaging (MRI) and computed tomography (CT) scan, on the other hand, offer excellent anatomic detail but are less sensitive because they do not provide functional detail. Fusion imaging combines functional studies with morphological ones, so overcoming the drawbacks of both modalities. Software-based fusion of independently performed scintigraphic and radiological images has proven time consuming and impractical for routine use. Recently, dual-modality integrated imaging systems (SPECT/CT and PET/CT) have been developed: the acquired images are coregistered by means of the hardware in the same session. These new devices can be particularly useful for tumour imaging. The anatomical images provide precise localization and allow the exclusion of disease in sites of physiologic tracers' accumulation for SPECT and PET findings. Hybrid imaging in oncological applications has been very encouraging, indicating that these systems are suited for routine use in clinical practice. In fact, fused images provide additional information that improves diagnostic accuracy and impacts on patient management.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/50 - Scienze Tecniche Mediche Applicate
English
Con Impact Factor ISI
CT; Fusion imaging; Hybrid systems; PET; SPECT
fluorodeoxyglucose; pentetreotide in 111; tetrofosmin tc 99m; tracer; adult; aged; cancer diagnosis; cancer localization; cancer patient; computer assisted tomography; computer program; diagnostic accuracy; diagnostic imaging; human; male; nuclear magnetic resonance imaging; positron emission tomography; priority journal; review; scintiscanning; sensitivity and specificity; single photon emission computer tomography; Diagnostic Imaging; Humans; Image Processing, Computer-Assisted; Medical Oncology; Nuclear Medicine; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon
Schillaci, O., Simonetti, G. (2004). Fusion imaging in nuclear medicine - Applications of dual-modality systems in oncology. CANCER BIOTHERAPY & RADIOPHARMACEUTICALS, 19(1), 1-10 [10.1089/108497804773391621].
Schillaci, O; Simonetti, Gme
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/56512
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