The interactions between sleep and epilepsy are well known. A nodal point of the relationship between sleep and epilepsy is represented by pharmacological treatment. Sleep disturbances such as drowsiness are among the most frequent side effects of treatment with antiepileptic drugs, since they can deeply modify both sleep architecture and the sleep-wake cycle. Severe daytime somnolence affects patients' activities and it may facilitate the occurrence of seizures. These considerations underline the importance of antiepileptic drugs having anticonvulsant properties that do not negatively influence sleep and daytime somnolence. In this paper we review some relevant aspects of the effects of antiepileptic drugs on sleep. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

Placidi F., S.A. (2000). Effect of antiepileptic drugs on sleep. CLINICAL NEUROPHYSIOLOGY, 111(SUPPL. 2), S115-S119 [10.1016/S1388-2457(00)00411-9].

Effect of antiepileptic drugs on sleep

PLACIDI, FABIO;MARCIANI, MARIA GRAZIA;DIOMEDI, MARINA;
2000

Abstract

The interactions between sleep and epilepsy are well known. A nodal point of the relationship between sleep and epilepsy is represented by pharmacological treatment. Sleep disturbances such as drowsiness are among the most frequent side effects of treatment with antiepileptic drugs, since they can deeply modify both sleep architecture and the sleep-wake cycle. Severe daytime somnolence affects patients' activities and it may facilitate the occurrence of seizures. These considerations underline the importance of antiepileptic drugs having anticonvulsant properties that do not negatively influence sleep and daytime somnolence. In this paper we review some relevant aspects of the effects of antiepileptic drugs on sleep. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/26 - Neurologia
English
Con Impact Factor ISI
Antiepileptic drugs; Epilepsy; Polysomnography; Sleep
anticonvulsive agent; benzodiazepine derivative; carbamazepine; ethosuximide; felbamate; gabapentin; lamotrigine; phenobarbital; phenytoin; tiagabine; topiramate; valproic acid; vigabatrin; article; drug effect; drug efficacy; drug mechanism; epilepsy; human; monotherapy; priority journal; quality of life; sleep pattern; sleep waking cycle; somnolence; Anticonvulsants; Epilepsy; Human; Sleep
Placidi F., S.A. (2000). Effect of antiepileptic drugs on sleep. CLINICAL NEUROPHYSIOLOGY, 111(SUPPL. 2), S115-S119 [10.1016/S1388-2457(00)00411-9].
Placidi, F; Scalise, A; Marciani, Mg; Romigi, A; Diomedi, M; Gigli, Gl
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/56120
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