Endogenous protein phosphorylation by cyclic AMP-dependent protein kinase was found reduced in striatal membranes obtained from chronic ethanol-treated rats. Experiments using an exogenous substrate show that the decreased response is due to a deficiency in the phosphorylating activity of the cyclic AMP-dependent protein kinase and not to a lack of endogenous substrate for phosphorylation.

Rius, R., Govoni, S., Battaini, F.m., Trabucchi, M.m. (1986). Cyclic AMP-dependent protein phosphorylation is reduced in rat striatum after chronic ethanol treatment. BRAIN RESEARCH, 365(2), 355-359.

Cyclic AMP-dependent protein phosphorylation is reduced in rat striatum after chronic ethanol treatment

BATTAINI, FIORENZO MARIA;TRABUCCHI, MARCO MARIO
1986-02-19

Abstract

Endogenous protein phosphorylation by cyclic AMP-dependent protein kinase was found reduced in striatal membranes obtained from chronic ethanol-treated rats. Experiments using an exogenous substrate show that the decreased response is due to a deficiency in the phosphorylating activity of the cyclic AMP-dependent protein kinase and not to a lack of endogenous substrate for phosphorylation.
19-feb-1986
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/14 - FARMACOLOGIA
English
Con Impact Factor ISI
Caudate Nucleus; Male; Cyclic AMP; Rats, Inbred Strains; Alcoholism; Nerve Tissue Proteins; Rats; Protein Kinases; Phosphorylation; Autoradiography; Animals; Dopamine
Rius, R., Govoni, S., Battaini, F.m., Trabucchi, M.m. (1986). Cyclic AMP-dependent protein phosphorylation is reduced in rat striatum after chronic ethanol treatment. BRAIN RESEARCH, 365(2), 355-359.
Rius, R; Govoni, S; Battaini, Fm; Trabucchi, Mm
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/55683
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