Endogenous protein phosphorylation by cyclic AMP-dependent protein kinase was found reduced in striatal membranes obtained from chronic ethanol-treated rats. Experiments using an exogenous substrate show that the decreased response is due to a deficiency in the phosphorylating activity of the cyclic AMP-dependent protein kinase and not to a lack of endogenous substrate for phosphorylation.
Rius, R., Govoni, S., Battaini, F.m., Trabucchi, M.m. (1986). Cyclic AMP-dependent protein phosphorylation is reduced in rat striatum after chronic ethanol treatment. BRAIN RESEARCH, 365(2), 355-359.
Cyclic AMP-dependent protein phosphorylation is reduced in rat striatum after chronic ethanol treatment
BATTAINI, FIORENZO MARIA;TRABUCCHI, MARCO MARIO
1986-02-19
Abstract
Endogenous protein phosphorylation by cyclic AMP-dependent protein kinase was found reduced in striatal membranes obtained from chronic ethanol-treated rats. Experiments using an exogenous substrate show that the decreased response is due to a deficiency in the phosphorylating activity of the cyclic AMP-dependent protein kinase and not to a lack of endogenous substrate for phosphorylation.File in questo prodotto:
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