Neurotensin immunoreactivity (NT-IR) is significantly reduced in striatum, nucleus accumbens and hippocampus but not in frontal cortex, hypothalamus and septum of 24-month-old male Sprague Dawley rats. Neurotensin binding in cortex, striatum, hypothalamus and hippocampus shows a rather uniform decline with age. The changes in NT-IR content in striatum and nucleus accumbens are of particular interest in view of the existence of a functional relationship between dopamine and neurotensin.

Govoni, S., Di Giovine, S., Battaini, F.m., Trabucchi, M.m. (1986). Age-related changes in neurotensin content and receptors in various rat brain areas. EXPERIMENTAL AGING RESEARCH, 12(4), 197-201.

Age-related changes in neurotensin content and receptors in various rat brain areas

BATTAINI, FIORENZO MARIA;TRABUCCHI, MARCO MARIO
1986-01-01

Abstract

Neurotensin immunoreactivity (NT-IR) is significantly reduced in striatum, nucleus accumbens and hippocampus but not in frontal cortex, hypothalamus and septum of 24-month-old male Sprague Dawley rats. Neurotensin binding in cortex, striatum, hypothalamus and hippocampus shows a rather uniform decline with age. The changes in NT-IR content in striatum and nucleus accumbens are of particular interest in view of the existence of a functional relationship between dopamine and neurotensin.
1986
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/14 - FARMACOLOGIA
English
Con Impact Factor ISI
Hippocampus; Neurotensin; Corpus Striatum; Male; Hypothalamus; Nucleus Accumbens; Frontal Lobe; Rats; Animals; Brain Chemistry; Rats, Inbred Strains; Aging; Dopamine
Govoni, S., Di Giovine, S., Battaini, F.m., Trabucchi, M.m. (1986). Age-related changes in neurotensin content and receptors in various rat brain areas. EXPERIMENTAL AGING RESEARCH, 12(4), 197-201.
Govoni, S; Di Giovine, S; Battaini, Fm; Trabucchi, Mm
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/55682
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