The effect of short term and long term ischemia induced by right carotid occlusion was studied on beta-adrenergic receptor function in rat cerebral microvessels. The results show a different time-dependent responsiveness of the two hemispheres to ischemia, with a pronounced and more persistent decrease in the number of capillary beta-receptors in the left side of the brain. The data suggest the existence of asymmetries in the control of brain microvasculature which may mediate the different time-course of beta-receptor changes in response to ischemia.

Magnoni, M., Frattola, L., Pasinetti, G., Govoni, S., Battaini, F.m., Trabucchi, M.m. (1986). Time-related asymmetric changes of brain microvessel beta-adrenergic receptors in the two hemispheres after carotid occlusion. STROKE, 17(5), 966-969.

Time-related asymmetric changes of brain microvessel beta-adrenergic receptors in the two hemispheres after carotid occlusion

BATTAINI, FIORENZO MARIA;TRABUCCHI, MARCO MARIO
1986-01-01

Abstract

The effect of short term and long term ischemia induced by right carotid occlusion was studied on beta-adrenergic receptor function in rat cerebral microvessels. The results show a different time-dependent responsiveness of the two hemispheres to ischemia, with a pronounced and more persistent decrease in the number of capillary beta-receptors in the left side of the brain. The data suggest the existence of asymmetries in the control of brain microvasculature which may mediate the different time-course of beta-receptor changes in response to ischemia.
1986
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/14 - FARMACOLOGIA
English
Con Impact Factor ISI
Male; Time Factors; Microcirculation; Pindolol; Rats; Animals; Iodocyanopindolol; Binding Sites; Kinetics; Capillaries; Ischemic Attack, Transient; Rats, Inbred Strains; Receptors, Adrenergic, beta; Cerebrovascular Circulation; Carotid Artery Diseases
Magnoni, M., Frattola, L., Pasinetti, G., Govoni, S., Battaini, F.m., Trabucchi, M.m. (1986). Time-related asymmetric changes of brain microvessel beta-adrenergic receptors in the two hemispheres after carotid occlusion. STROKE, 17(5), 966-969.
Magnoni, M; Frattola, L; Pasinetti, G; Govoni, S; Battaini, Fm; Trabucchi, Mm
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/55647
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