In order to characterize the biological effects and molecular mechanism underlying indocyanine-green (ICG)-mediated photo-oxidative cell damage, human cultured retinal pigmented epithelium (RPE) cells preloaded with ICG were exposed to 810-nm laser irradiation. Cell viability and death induction were examined, as well as the modulation of proteins involved in cell death and DNA repair.
Ricci, F., Pucci, S., Sesti, F., Missiroli, F., Cerulli, L., Spagnoli, L. (2007). Modulation of Ku70/80, clusterin/ApoJ isoforms and Bax expression in indocyanine-green-mediated photo-oxidative cell damage. OPHTHALMIC RESEARCH, 39(3), 164-173 [10.1159/000103236].
Modulation of Ku70/80, clusterin/ApoJ isoforms and Bax expression in indocyanine-green-mediated photo-oxidative cell damage
RICCI, FEDERICO;PUCCI, SABINA;MISSIROLI, FILIPPO;CERULLI, LUCIANO;
2007-01-01
Abstract
In order to characterize the biological effects and molecular mechanism underlying indocyanine-green (ICG)-mediated photo-oxidative cell damage, human cultured retinal pigmented epithelium (RPE) cells preloaded with ICG were exposed to 810-nm laser irradiation. Cell viability and death induction were examined, as well as the modulation of proteins involved in cell death and DNA repair.| File | Dimensione | Formato | |
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