The functional properties of hemoglobin from the whale Balaenoptera acutorostrata have been characterized as a function of pH, CO2, organic phosphates and temperature. Carbon dioxide effect does not depend on the presence of organic phosphates such as 2,3-DPG and P6-inositol while it is strongly affected by temperature, so that at 37 degrees C it is completely abolished. This, together with the very small delta H of oxygen binding (delta H = -4 to -2 Kcal/mol of oxygen at pH 7.4) has been physiologically interpreted on the basis of the specific metabolic needs of fins and tail which are the place of a great muscular activity.
Giardina, B., Ekker, M., Condo', S.g., Scatena, R., Clementi, M., Brix, O. (1990). Arctic adaptation in whale hemoglobin: interplay of carbon dioxide and temperature in the oxygen unloading. ARCTIC MEDICAL RESEARCH, 49(2), 93-97.
Arctic adaptation in whale hemoglobin: interplay of carbon dioxide and temperature in the oxygen unloading
CONDO', SAVERIO GIOVANNI;
1990-04-01
Abstract
The functional properties of hemoglobin from the whale Balaenoptera acutorostrata have been characterized as a function of pH, CO2, organic phosphates and temperature. Carbon dioxide effect does not depend on the presence of organic phosphates such as 2,3-DPG and P6-inositol while it is strongly affected by temperature, so that at 37 degrees C it is completely abolished. This, together with the very small delta H of oxygen binding (delta H = -4 to -2 Kcal/mol of oxygen at pH 7.4) has been physiologically interpreted on the basis of the specific metabolic needs of fins and tail which are the place of a great muscular activity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
