PR8 virus depressed interleukin-2 (IL-2) and natural killer (NK) cell activity in BALB/c infected mice. IL-2 production was not dependent on (i) a decreased number of T cells or (ii) a primary defect in IL-1 production, but on a T-suppressor cell subpopulation. In fact, when T suppressor cells were removed from infected spleen cells, we observed normal levels of IL-2 activity.

Del Gobbo V., V.N. (1990). Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice. IMMUNOLOGY, 69(3), 454-459.

Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice

DEL GOBBO, VERA;MARINI, STEFANO;BALESTRA, EMANUELA;
1990

Abstract

PR8 virus depressed interleukin-2 (IL-2) and natural killer (NK) cell activity in BALB/c infected mice. IL-2 production was not dependent on (i) a decreased number of T cells or (ii) a primary defect in IL-1 production, but on a T-suppressor cell subpopulation. In fact, when T suppressor cells were removed from infected spleen cells, we observed normal levels of IL-2 activity.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/10
eng
Con Impact Factor ISI
interleukin 2; animal cell; animal experiment; article; cell culture; influenza virus; natural killer cell; nonhuman; priority journal; suppressor cell; t lymphocyte; virus infection; Animal; Influenza; Interleukin-2; Killer Cells, Natural; Lymphocyte Depletion; Macrophages; Mice; Mice, Inbred BALB C; Spleen; Support, Non-U.S. Gov't; T-Lymphocytes, Suppressor-Effector
Del Gobbo V., V.N. (1990). Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice. IMMUNOLOGY, 69(3), 454-459.
DEL GOBBO, V; Villani, N; Marini, S; Balestra, E; Calio, R
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/53101
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