Androgen antagonists inhibit prostatic cell proliferation in normal and pathological conditions and are useful antitumor agents in prostatic carcinoma (PCa). Bicalutamide (BCLT) is a well-known non-steroidal antiandrogenic agent able to interfere with androgen receptor (AR). We tested the efficacy of BCLT in inhibiting proliferation of human PCa cell lines and of primary cultures from biopsies of PCa patients.

Vicentini, C., Festuccia, C., Angelucci, A., Gravina, G., Muzi, P., Eleuterio, E., et al. (2002). Bicalutamide dose-dependently inhibits proliferation in human prostatic carcinoma cell lines and primary cultures. ANTICANCER RESEARCH, 22(5), 2917-2922.

Bicalutamide dose-dependently inhibits proliferation in human prostatic carcinoma cell lines and primary cultures

MIANO, ROBERTO;
2002-01-01

Abstract

Androgen antagonists inhibit prostatic cell proliferation in normal and pathological conditions and are useful antitumor agents in prostatic carcinoma (PCa). Bicalutamide (BCLT) is a well-known non-steroidal antiandrogenic agent able to interfere with androgen receptor (AR). We tested the efficacy of BCLT in inhibiting proliferation of human PCa cell lines and of primary cultures from biopsies of PCa patients.
2002
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/24 - UROLOGIA
English
Con Impact Factor ISI
Anilides; Antineoplastic Agents; Dose-Response Relationship, Drug; Humans; Fluorescent Dyes; Ethidium; Tosyl Compounds; Acridine Orange; Nitriles; Androgen Antagonists; Tumor Cells, Cultured; Inhibitory Concentration 50; Staining and Labeling; Prostatic Neoplasms; Male; Cell Division
Vicentini, C., Festuccia, C., Angelucci, A., Gravina, G., Muzi, P., Eleuterio, E., et al. (2002). Bicalutamide dose-dependently inhibits proliferation in human prostatic carcinoma cell lines and primary cultures. ANTICANCER RESEARCH, 22(5), 2917-2922.
Vicentini, C; Festuccia, C; Angelucci, A; Gravina, G; Muzi, P; Eleuterio, E; Miano, R; Marronaro, A; Tubaro, A; Bologna, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/53020
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